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Organic compounds with acidic properties, and will commonly have carboxylic acids or similar functional groups in their structure. Derived compounds are also included.
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3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker. It is used in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs achieve this by connecting two different ligands: one for an E3 ubiquitin ligase and the other for the target protein.
Alkyl/ether-based PROTAC linker
Used in the synthesis of PROTACs
Designed to exploit the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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